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A Novel Extrinsic Pathway for Apoptosis by Tumor Suppressor Par-4
Prostate apoptosis response-4 (Par-4) is a pro-apoptotic protein with intracellular functions in the cytoplasm and nucleus. Unexpectedly, we noted Par-4 protein is spontaneously secreted by normal and cancer cells in culture, and by Par-4 transgenic mice that are resistant to spontaneous tumors. Sho...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774252/ https://ncbi.nlm.nih.gov/pubmed/19632185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.05.022 |
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