A Novel Extrinsic Pathway for Apoptosis by Tumor Suppressor Par-4

Prostate apoptosis response-4 (Par-4) is a pro-apoptotic protein with intracellular functions in the cytoplasm and nucleus. Unexpectedly, we noted Par-4 protein is spontaneously secreted by normal and cancer cells in culture, and by Par-4 transgenic mice that are resistant to spontaneous tumors. Sho...

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Bibliografiske detaljer
Main Authors: Burikhanov, Ravshan, Zhao, Yanming, Goswami, Anindya, Qiu, Shirley, Schwarze, Steve, Rangnekar, Vivek M.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774252/
https://ncbi.nlm.nih.gov/pubmed/19632185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.05.022
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