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Novel Mechanism of Apoptosis Resistance in Cancer Mediated by Extracellular PAR-4
Tumor suppressor PAR-4 acts in part by modulating sensitivity to apoptosis but the basis for its activity is not fully understood. In this study, we describe a novel mechanism of anti-apoptosis by NF-kappaB, revealing that it can block PAR-4-mediated apoptosis by downregulating trafficking of the PA...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549021/ https://ncbi.nlm.nih.gov/pubmed/23204231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3212 |
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