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Mechanisms of Apoptosis by the Tumor Suppressor Par-4

Par-4 is a pro-apoptotic, tumor suppressor protein that induces apoptosis selectively in cancer cells. Endoplasmic reticulum-stress and higher levels of protein kinase A in tumor cells confer the coveted feature of cancer selective response to extracellular and intracellular Par-4, respectively. Rec...

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Detalhes bibliográficos
Main Authors: Hebbar, Nikhil, Wang, Chi, Rangnekar, Vivek M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414654/
https://ncbi.nlm.nih.gov/pubmed/22552839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24098
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