Polysialic Acid Directs Tumor Cell Growth by Controlling Heterophilic Neural Cell Adhesion Molecule Interactions

Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), promotes neural plasticity and tumor malignancy, but its mode of action is controversial. Here we establish that PSA controls tumor cell growth and differentiation by interfering with NCAM signaling a...

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Bibliografski detalji
Glavni autori: Seidenfaden, Ralph, Krauter, Andrea, Schertzinger, Frank, Gerardy-Schahn, Rita, Hildebrandt, Herbert
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Cell Growth and Development
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC166353/
https://ncbi.nlm.nih.gov/pubmed/12897159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.16.5908-5918.2003
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