Neural Cell Adhesion Molecule-Associated Polysialic Acid Regulates Synaptic Plasticity and Learning by Restraining the Signaling through GluN2B-Containing NMDA Receptors

The neural cell adhesion molecule (NCAM) is the predominant carrier of α2,8 polysialic acid (PSA) in the mammalian brain. Abnormalities in PSA and NCAM expression are associated with schizophrenia in humans and cause deficits in hippocampal synaptic plasticity and contextual fear conditioning in mic...

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Vydáno v:J Neurosci
Hlavní autoři: Kochlamazashvili, Gaga, Senkov, Oleg, Grebenyuk, Sergei, Robinson, Catrina, Xiao, Mei-Fang, Stummeyer, Katharina, Gerardy-Schahn, Rita, Engel, Andreas K., Feig, Larry, Semyanov, Alexey, Suppiramaniam, Vishnu, Schachner, Melitta, Dityatev, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390116/
https://ncbi.nlm.nih.gov/pubmed/20237287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5806-09.2010
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