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Polysialic Acid Directs Tumor Cell Growth by Controlling Heterophilic Neural Cell Adhesion Molecule Interactions

Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), promotes neural plasticity and tumor malignancy, but its mode of action is controversial. Here we establish that PSA controls tumor cell growth and differentiation by interfering with NCAM signaling a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Seidenfaden, Ralph, Krauter, Andrea, Schertzinger, Frank, Gerardy-Schahn, Rita, Hildebrandt, Herbert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC166353/
https://ncbi.nlm.nih.gov/pubmed/12897159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.16.5908-5918.2003
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