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Increased T cell reactivity to amyloid β protein in older humans and patients with Alzheimer disease
Alzheimer disease (AD) is characterized by the progressive deposition of the 42-residue amyloid β protein (Aβ) in brain regions serving memory and cognition. In animal models of AD, immunization with Aβ results in the clearance of Aβ deposits from the brain. However, a trial of vaccination with synt...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166296/ https://ncbi.nlm.nih.gov/pubmed/12897209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318104 |
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