Increased T cell reactivity to amyloid β protein in older humans and patients with Alzheimer disease

Alzheimer disease (AD) is characterized by the progressive deposition of the 42-residue amyloid β protein (Aβ) in brain regions serving memory and cognition. In animal models of AD, immunization with Aβ results in the clearance of Aβ deposits from the brain. However, a trial of vaccination with synt...

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Detalhes bibliográficos
Main Authors: Monsonego, Alon, Zota, Victor, Karni, Arnon, Krieger, Jeffery I., Bar-Or, Amit, Bitan, Gal, Budson, Andrew E., Sperling, Reisa, Selkoe, Dennis J., Weiner, Howard L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166296/
https://ncbi.nlm.nih.gov/pubmed/12897209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318104
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