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Spatial Relationship Between Synapse Loss and β-Amyloid Deposition in Tg2576 Mice

Although there is evidence that β-amyloid impairs synaptic function, the relationship between β-amyloid and synapse loss is not well understood. In this study, we assessed synapse density within the hippocampus and the entorhinal cortex of Tg2576 mice at 6–18 months of age using stereological method...

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Détails bibliographiques
Auteurs principaux: Dong, Hongxin, Martin, Maureen V., Chambers, Shawn, Csernansky, John G.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1661843/
https://ncbi.nlm.nih.gov/pubmed/17111375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.21176
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