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Structural Studies of Human Naked2: A Biologically Active Intrinsically Unstructured Protein

Naked1 and 2 are two mammalian orthologs of Naked Cuticle, a canonical Wnt signaling antagonist in Drosophila. Naked2, but not Naked1, interacts with transforming growth factor-α (TGFα) and escorts TGFα-containing vesicles to the basolateral membrane of polarized epithelial cells. Full-length Naked2...

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Main Authors: Hu, Tianhui, Krezel, Andrzej M, Li, Cunxi, Coffey, Robert J
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1661664/
https://ncbi.nlm.nih.gov/pubmed/17045239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.09.121
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