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EGF receptor-independent action of TGF-α protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation

Naked family members (Drosophila Naked Cuticle and mammalian Naked1 and Naked2) have been identified as inducible antagonists of canonical Wnt signaling. We recently reported that Naked2, but not Naked1, interacts with the cytoplasmic tail of TGF-α, thereby coating TGF-α-containing exocytic vesicles...

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Detalhes bibliográficos
Main Authors: Ding, Wei, Li, Cunxi, Hu, Tianhui, Graves-Deal, Ramona, Fotia, Andrew B., Weissman, Allan M., Coffey, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527346/
https://ncbi.nlm.nih.gov/pubmed/18757723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806298105
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