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The C Terminus of YopT Is Crucial for Activity and the N Terminus Is Crucial for Substrate Binding
Recently, it was shown that Yersinia outer protein T (YopT) belongs to a new family of cysteine proteases containing invariant C, H, and D residues that are crucial for its activity. YopT cleaves RhoA, Rac, and Cdc42 at their C termini, thereby releasing them from the membrane. Moreover, YopT inhibi...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166019/ https://ncbi.nlm.nih.gov/pubmed/12874342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4623-4632.2003 |
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