The C Terminus of YopT Is Crucial for Activity and the N Terminus Is Crucial for Substrate Binding

Recently, it was shown that Yersinia outer protein T (YopT) belongs to a new family of cysteine proteases containing invariant C, H, and D residues that are crucial for its activity. YopT cleaves RhoA, Rac, and Cdc42 at their C termini, thereby releasing them from the membrane. Moreover, YopT inhibi...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Εκδόθηκε σε:	Infect Immun
Κύριοι συγγραφείς:	Sorg, Isabel, Hoffmann, Claudia, Dumbach, Juergen, Aktories, Klaus, Schmidt, Gudula
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 2003
Θέματα:	Molecular Pathogenesis
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12874342/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.8.4623-4632.2003
Ετικέτες:	Προσθήκη ετικέτας Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!