The Mycobacterium tuberculosis 19-Kilodalton Lipoprotein Inhibits Gamma Interferon-Regulated HLA-DR and FcγR1 on Human Macrophages through Toll-Like Receptor 2

Mycobacterium tuberculosis survives in macrophages in the face of acquired CD4(+) T-cell immunity, which controls but does not eliminate the organism. Gamma interferon (IFN-γ) has a central role in host defenses against M. tuberculosis by activating macrophages and regulating major histocompatibilit...

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Detalhes bibliográficos
Main Authors: Gehring, Adam J., Rojas, Roxana E., Canaday, David H., Lakey, David L., Harding, Clifford V., Boom, W. Henry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166015/
https://ncbi.nlm.nih.gov/pubmed/12874328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4487-4497.2003
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