Polymorphisms in the Fc Gamma Receptor IIIA and Toll-Like Receptor 9 Are Associated with Protection against Severe Malarial Anemia and Changes in Circulating Gamma Interferon Levels

An understanding of the immunogenetic basis of naturally acquired immunity to Plasmodium falciparum infection would aid in the designing of a rationally based malaria vaccine. Variants within the Fc gamma receptors (FcγRs) mediate immunity through engagement of immunoglobulin G and other immune medi...

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Main Authors: Munde, Elly O., Okeyo, Winnie A., Anyona, Samwel B., Raballah, Evans, Konah, Stephen, Okumu, Wilson, Ogonda, Lilian, Vulule, John, Ouma, Collins
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2012
Ábhair:
Host Response and Inflammation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497437/
https://ncbi.nlm.nih.gov/pubmed/23045477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00945-12
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