Polymorphisms in the Fc Gamma Receptor IIIA and Toll-Like Receptor 9 Are Associated with Protection against Severe Malarial Anemia and Changes in Circulating Gamma Interferon Levels

An understanding of the immunogenetic basis of naturally acquired immunity to Plasmodium falciparum infection would aid in the designing of a rationally based malaria vaccine. Variants within the Fc gamma receptors (FcγRs) mediate immunity through engagement of immunoglobulin G and other immune medi...

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Bibliographic Details
Main Authors: Munde, Elly O., Okeyo, Winnie A., Anyona, Samwel B., Raballah, Evans, Konah, Stephen, Okumu, Wilson, Ogonda, Lilian, Vulule, John, Ouma, Collins
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497437/
https://ncbi.nlm.nih.gov/pubmed/23045477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00945-12
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