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Toll-Like Receptor 2- and 6-Mediated Stimulation by Macrophage-Activating Lipopeptide 2 Induces Lipopolysaccharide (LPS) Cross Tolerance in Mice, Which Results in Protection from Tumor Necrosis Factor Alpha but in Only Partial Protection from Lethal LPS Doses

Patients or experimental animals previously exposed to lipopolysaccharide (LPS) become tolerant to further LPS challenge. We investigated the potential of the macrophage-activating lipopeptide 2 (MALP-2) to induce in vivo cross tolerance to tumor necrosis factor alpha (TNF-α) and LPS. MALP-2-induced...

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Bibliografiset tiedot
Päätekijät: Deiters, Ursula, Gumenscheimer, Marina, Galanos, Chris, Mühlradt, Peter F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC166003/
https://ncbi.nlm.nih.gov/pubmed/12874325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4456-4462.2003
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