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Monocyte chemoattractant protein 1 in obesity and insulin resistance

This study identifies monocyte chemoattractant protein 1 (MCP-1) as an insulin-responsive gene. It also shows that insulin induces substantial expression and secretion of MCP-1 both in vitro in insulin-resistant (IR) 3T3-L1 adipocytes and in vivo in IR obese mice (ob/ob). Thus, MCP-1 resembles other...

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Detalhes bibliográficos
Main Authors: Sartipy, Peter, Loskutoff, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165864/
https://ncbi.nlm.nih.gov/pubmed/12756299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1133870100
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