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Mechanism of Fluconazole Resistance in Candida albicans Biofilms: Phase-Specific Role of Efflux Pumps and Membrane Sterols

Candida albicans biofilms are formed through three distinct developmental phases and are associated with high fluconazole (FLU) resistance. In the present study, we used a set of isogenic Candida strains lacking one or more of the drug efflux pumps Cdr1p, Cdr2p, and Mdr1p to determine their role in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Infect Immun
Prif Awduron: Mukherjee, Pranab K., Chandra, Jyotsna, Kuhn, Duncan M., Ghannoum, Mahmoud A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165995/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12874310/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.8.4333-4340.2003
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