Mechanism of Fluconazole Resistance in Candida albicans Biofilms: Phase-Specific Role of Efflux Pumps and Membrane Sterols

Candida albicans biofilms are formed through three distinct developmental phases and are associated with high fluconazole (FLU) resistance. In the present study, we used a set of isogenic Candida strains lacking one or more of the drug efflux pumps Cdr1p, Cdr2p, and Mdr1p to determine their role in...

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הוצא לאור ב:	Infect Immun
Principais autores:	Mukherjee, Pranab K., Chandra, Jyotsna, Kuhn, Duncan M., Ghannoum, Mahmoud A.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2003
נושאים:	Fungal and Parasitic Infections
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12874310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.8.4333-4340.2003
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