Mechanism of Fluconazole Resistance in Candida albicans Biofilms: Phase-Specific Role of Efflux Pumps and Membrane Sterols

Candida albicans biofilms are formed through three distinct developmental phases and are associated with high fluconazole (FLU) resistance. In the present study, we used a set of isogenic Candida strains lacking one or more of the drug efflux pumps Cdr1p, Cdr2p, and Mdr1p to determine their role in...

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Bibliografische gegevens

Gepubliceerd in:	Infect Immun
Hoofdauteurs:	Mukherjee, Pranab K., Chandra, Jyotsna, Kuhn, Duncan M., Ghannoum, Mahmoud A.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 2003
Onderwerpen:	Fungal and Parasitic Infections
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165995/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12874310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.8.4333-4340.2003
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