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Mechanism of Fluconazole Resistance in Candida albicans Biofilms: Phase-Specific Role of Efflux Pumps and Membrane Sterols

Candida albicans biofilms are formed through three distinct developmental phases and are associated with high fluconazole (FLU) resistance. In the present study, we used a set of isogenic Candida strains lacking one or more of the drug efflux pumps Cdr1p, Cdr2p, and Mdr1p to determine their role in...

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Detaylı Bibliyografya
Asıl Yazarlar: Mukherjee, Pranab K., Chandra, Jyotsna, Kuhn, Duncan M., Ghannoum, Mahmoud A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC165995/
https://ncbi.nlm.nih.gov/pubmed/12874310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.8.4333-4340.2003
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