Effect of Complement Component C3 Deficiency on Experimental Lyme Borreliosis in Mice

Mice deficient in complement component C3 (C3(−/−)) and syngeneic C57BL/6 control mice were challenged with Borrelia burgdorferi to determine the role of complement in immune clearance and joint histopathology during experimental Lyme borreliosis. Tibiotarsal joint, ear, and heart tissues were monit...

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Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Lawrenz, Matthew B., Wooten, R. Mark, Zachary, James F., Drouin, Scott M., Weis, Janis J., Wetsel, Rick A., Norris, Steven J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Host Response and Inflammation
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165993/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12874322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.8.4432-4440.2003
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