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Effect of Complement Component C3 Deficiency on Experimental Lyme Borreliosis in Mice

Mice deficient in complement component C3 (C3(−/−)) and syngeneic C57BL/6 control mice were challenged with Borrelia burgdorferi to determine the role of complement in immune clearance and joint histopathology during experimental Lyme borreliosis. Tibiotarsal joint, ear, and heart tissues were monit...

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Publicado en:Infect Immun
Principais autores: Lawrenz, Matthew B., Wooten, R. Mark, Zachary, James F., Drouin, Scott M., Weis, Janis J., Wetsel, Rick A., Norris, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2003
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165993/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12874322/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.8.4432-4440.2003
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