Effect of Complement Component C3 Deficiency on Experimental Lyme Borreliosis in Mice

Mice deficient in complement component C3 (C3(−/−)) and syngeneic C57BL/6 control mice were challenged with Borrelia burgdorferi to determine the role of complement in immune clearance and joint histopathology during experimental Lyme borreliosis. Tibiotarsal joint, ear, and heart tissues were monit...

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הוצא לאור ב:	Infect Immun
Principais autores:	Lawrenz, Matthew B., Wooten, R. Mark, Zachary, James F., Drouin, Scott M., Weis, Janis J., Wetsel, Rick A., Norris, Steven J.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2003
נושאים:	Host Response and Inflammation
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165993/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12874322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.8.4432-4440.2003
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