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Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion
Enforced expression of growth factor independent 1 (Gfi-1), a transcription repressor induced by T cell activation and IL-4/Stat6 signaling, strikingly enhances Th2 cell expansion. Using conditionally Gfi1-deficient mice prepared for this study, we show that in vitro or in vivo deletion of this fact...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1654136/ https://ncbi.nlm.nih.gov/pubmed/17116877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608981103 |
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