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Interleukin 2 plays a central role in Th2 differentiation

Differentiation of naïve CD4 T cells into T helper (Th) 2 cells requires signaling through the T cell receptor and an appropriate cytokine environment. IL-4 is critical for such Th2 differentiation. We show that IL-2 plays a central role in this process. The effect of IL-2 on Th2 generation does not...

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Detalhes bibliográficos
Main Authors: Cote-Sierra, Javier, Foucras, Gilles, Guo, Liying, Chiodetti, Lynda, Young, Howard A., Hu-Li, Jane, Zhu, Jinfang, Paul, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC374338/
https://ncbi.nlm.nih.gov/pubmed/15004274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400339101
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