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In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production
TH2 clones may produce very variable amounts of IL-4. Among six TH2 clones prepared from homozygous or heterozygous mice in which Gfp replaced the first exon of Il4, a range of patterns of CpG methylation in the Il4/Il13 locus was observed correlating with the degree of expression of IL-4 or green f...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124993/ https://ncbi.nlm.nih.gov/pubmed/12149469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162360199 |
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