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Native topology determines force-induced unfolding pathways in globular proteins
Single-molecule manipulation techniques reveal that stretching unravels individually folded domains in the muscle protein titin and the extracellular matrix protein tenascin. These elastic proteins contain tandem repeats of folded domains with β-sandwich architecture. Herein, we propose by stretchin...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The National Academy of Sciences
2000
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC16532/ https://ncbi.nlm.nih.gov/pubmed/10860990 |
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