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Native topology determines force-induced unfolding pathways in globular proteins

Single-molecule manipulation techniques reveal that stretching unravels individually folded domains in the muscle protein titin and the extracellular matrix protein tenascin. These elastic proteins contain tandem repeats of folded domains with β-sandwich architecture. Herein, we propose by stretchin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Klimov, D. K., Thirumalai, D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC16532/
https://ncbi.nlm.nih.gov/pubmed/10860990
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