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Force-dependent switch in protein unfolding pathways and transition-state movements
Although it is known that single-domain proteins fold and unfold by parallel pathways, demonstration of this expectation has been difficult to establish in experiments. Unfolding rate, [Formula: see text] , as a function of force f, obtained in single-molecule pulling experiments on src SH3 domain,...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4760810/ https://ncbi.nlm.nih.gov/pubmed/26818842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515730113 |
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