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Overexpression of the α-2,6-Sialyltransferase in MDCK Cells Increases Influenza Virus Sensitivity to Neuraminidase Inhibitors

No reliable cell culture assay is currently available for monitoring human influenza virus sensitivity to neuraminidase inhibitors (NAI). This can be explained by the observation that because of a low concentration of sialyl-α2,6-galactose (Sia[α2,6]Gal)-containing virus receptors in conventional ce...

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Détails bibliographiques
Auteurs principaux: Matrosovich, Mikhail, Matrosovich, Tatyana, Carr, Jackie, Roberts, Noel A., Klenk, Hans-Dieter
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC165236/
https://ncbi.nlm.nih.gov/pubmed/12857911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8418-8425.2003
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