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Overexpression of the α-2,6-Sialyltransferase in MDCK Cells Increases Influenza Virus Sensitivity to Neuraminidase Inhibitors

No reliable cell culture assay is currently available for monitoring human influenza virus sensitivity to neuraminidase inhibitors (NAI). This can be explained by the observation that because of a low concentration of sialyl-α2,6-galactose (Sia[α2,6]Gal)-containing virus receptors in conventional ce...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Matrosovich, Mikhail, Matrosovich, Tatyana, Carr, Jackie, Roberts, Noel A., Klenk, Hans-Dieter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165236/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12857911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.15.8418-8425.2003
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