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Molecular Mechanisms of Serum Resistance of Human Influenza H3N2 Virus and Their Involvement in Virus Adaptation in a New Host

H3N2 human influenza viruses that are resistant to horse, pig, or rabbit serum possess unique amino acid mutations in their hemagglutinin (HA) protein. To determine the molecular mechanisms of this resistance, we characterized the receptor-binding properties of these mutants by measuring their affin...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Matrosovich, Mikhail, Gao, Peng, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1998
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109785/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9658077/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.8.6373-6380.1998
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