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Molecular Mechanisms of Serum Resistance of Human Influenza H3N2 Virus and Their Involvement in Virus Adaptation in a New Host

H3N2 human influenza viruses that are resistant to horse, pig, or rabbit serum possess unique amino acid mutations in their hemagglutinin (HA) protein. To determine the molecular mechanisms of this resistance, we characterized the receptor-binding properties of these mutants by measuring their affin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Matrosovich, Mikhail, Gao, Peng, Kawaoka, Yoshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109785/
https://ncbi.nlm.nih.gov/pubmed/9658077
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