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Construction of an Expression System for Site-Directed Mutagenesis of the Lantibiotic Mersacidin
The lantibiotic (i.e., lanthionine-containing antibiotic) mersacidin is an antimicrobial peptide of 20 amino acids which is produced by Bacillus sp. strain HIL Y-85,54728. Mersacidin inhibits bacterial cell wall biosynthesis by binding to the precursor molecule lipid II. The structural gene of mersa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165212/ https://ncbi.nlm.nih.gov/pubmed/12839744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.7.3777-3783.2003 |
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