Construction of an Expression System for Site-Directed Mutagenesis of the Lantibiotic Mersacidin

The lantibiotic (i.e., lanthionine-containing antibiotic) mersacidin is an antimicrobial peptide of 20 amino acids which is produced by Bacillus sp. strain HIL Y-85,54728. Mersacidin inhibits bacterial cell wall biosynthesis by binding to the precursor molecule lipid II. The structural gene of mersa...

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Bibliographic Details

Published in:	Appl Environ Microbiol
Main Authors:	Szekat, Christiane, Jack, Ralph W., Skutlarek, Dirk, Färber, Harald, Bierbaum, Gabriele
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2003
Subjects:	Genetics and Molecular Biology
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC165212/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12839744/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.7.3777-3783.2003
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