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Construction of an Expression System for Site-Directed Mutagenesis of the Lantibiotic Mersacidin

The lantibiotic (i.e., lanthionine-containing antibiotic) mersacidin is an antimicrobial peptide of 20 amino acids which is produced by Bacillus sp. strain HIL Y-85,54728. Mersacidin inhibits bacterial cell wall biosynthesis by binding to the precursor molecule lipid II. The structural gene of mersa...

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Detalhes bibliográficos
Main Authors: Szekat, Christiane, Jack, Ralph W., Skutlarek, Dirk, Färber, Harald, Bierbaum, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165212/
https://ncbi.nlm.nih.gov/pubmed/12839744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.7.3777-3783.2003
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