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Receptor-mediated Regulation of PI3Ks Confines PI(3,4,5)P(3) to the Leading Edge of Chemotaxing Cells
Recent studies have demonstrated that PH domains specific for PI(3,4,5)P(3) accumulate at the leading edge of a number of migrating cells and that PI3Ks and PTEN associate with the membrane at the front and back, respectively, of chemotaxing Dictyostelium discoideum cells. However, the dependence of...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Cell Biology
2003
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC165086/ https://ncbi.nlm.nih.gov/pubmed/12802064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-10-0703 |
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