Receptor-mediated Regulation of PI3Ks Confines PI(3,4,5)P(3) to the Leading Edge of Chemotaxing Cells

Recent studies have demonstrated that PH domains specific for PI(3,4,5)P(3) accumulate at the leading edge of a number of migrating cells and that PI3Ks and PTEN associate with the membrane at the front and back, respectively, of chemotaxing Dictyostelium discoideum cells. However, the dependence of...

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Bibliografiset tiedot
Päätekijät: Huang, Yi Elaine, Iijima, Miho, Parent, Carole A., Funamoto, Satoru, Firtel, Richard A., Devreotes, Peter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2003
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC165086/
https://ncbi.nlm.nih.gov/pubmed/12802064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-10-0703
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