Comparative Analysis of the Escherichia coli Ketopantoate Hydroxymethyltransferase Crystal Structure Confirms that It Is a Member of the (βα)(8) Phosphoenolpyruvate/Pyruvate Superfamily

Escherichia coli ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first step in the biosynthesis pathway of pantothenate (vitamin B(5)), the transfer of a hydroxymethyl group onto α-ketoisovalerate. Here we describe a detailed comparative analysis of the KPHMT crystal structure and the id...

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Detalhes bibliográficos
Main Authors: Schmitzberger, Florian, Smith, Alison G., Abell, Chris, Blundell, Tom L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164873/
https://ncbi.nlm.nih.gov/pubmed/12837791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.14.4163-4171.2003
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