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Crystal structure of ketopantoate reductase from Thermococcus kodakarensis complexed with NADP(+)

Coenzyme A (CoA) plays pivotal roles in a variety of metabolic pathways in all organisms. The biosynthetic pathway of CoA is strictly regulated by feedback inhibition. In the hyperthermophilic archaeon Thermococcus kodakarensis, ketopantoate reductase (KPR), which catalyzes the NAD(P)H-dependent red...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Aikawa, Yoshiki, Nishitani, Yuichi, Tomita, Hiroya, Atomi, Haruyuki, Miki, Kunio
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854564/
https://ncbi.nlm.nih.gov/pubmed/27139828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16005033
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