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Crystal structure of ketopantoate reductase from Thermococcus kodakarensis complexed with NADP(+)

Coenzyme A (CoA) plays pivotal roles in a variety of metabolic pathways in all organisms. The biosynthetic pathway of CoA is strictly regulated by feedback inhibition. In the hyperthermophilic archaeon Thermococcus kodakarensis, ketopantoate reductase (KPR), which catalyzes the NAD(P)H-dependent red...

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Détails bibliographiques
Publié dans:Acta Crystallogr F Struct Biol Commun
Auteurs principaux: Aikawa, Yoshiki, Nishitani, Yuichi, Tomita, Hiroya, Atomi, Haruyuki, Miki, Kunio
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854564/
https://ncbi.nlm.nih.gov/pubmed/27139828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16005033
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