p53 Represses Cyclin D1 Transcription through Down Regulation of Bcl-3 and Inducing Increased Association of the p52 NF-κB Subunit with Histone Deacetylase 1

The p53 and NF-κB transcription factor families are important, multifunctional regulators of the cellular response to stress. Here we have investigated the regulatory mechanisms controlling p53-dependent cell cycle arrest and cross talk with NF-κB. Upon induction of p53 in H1299 or U-2 OS cells, we...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rocha, Sonia, Martin, Anthea M., Meek, David W., Perkins, Neil D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2003
Pynciau:
Transcriptional Regulation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC164841/
https://ncbi.nlm.nih.gov/pubmed/12808109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4713-4727.2003
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg