p53 Represses Cyclin D1 Transcription through Down Regulation of Bcl-3 and Inducing Increased Association of the p52 NF-κB Subunit with Histone Deacetylase 1

The p53 and NF-κB transcription factor families are important, multifunctional regulators of the cellular response to stress. Here we have investigated the regulatory mechanisms controlling p53-dependent cell cycle arrest and cross talk with NF-κB. Upon induction of p53 in H1299 or U-2 OS cells, we...

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Bibliographische Detailangaben
Hauptverfasser: Rocha, Sonia, Martin, Anthea M., Meek, David W., Perkins, Neil D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Transcriptional Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164841/
https://ncbi.nlm.nih.gov/pubmed/12808109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4713-4727.2003
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