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Episomal Persistence of Recombinant Adenoviral Vector Genomes during the Cell Cycle In Vivo
Previously we showed that recombinant adenoviral helper-dependent (HD) vectors result in long-term transgene expression levels in vivo which slowly declined by 95% over a period of 1 year. In this study, we further establish that this was not predominantly immune mediated. To determine if cell turno...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164819/ https://ncbi.nlm.nih.gov/pubmed/12805471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7689-7695.2003 |
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