Viral Escape from Dominant Simian Immunodeficiency Virus Epitope-Specific Cytotoxic T Lymphocytes in DNA-Vaccinated Rhesus Monkeys

Virus-specific cytotoxic T lymphocytes (CTL) are critical for control of human immunodeficiency virus type 1 replication. However, viral escape from CTL recognition can undermine this immune control. Here we demonstrate the high frequency and pattern of viral escape from dominant epitope-specific CT...

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Bibliografski detalji
Glavni autori: Barouch, Dan H., Kunstman, Jennifer, Glowczwskie, Jennifer, Kunstman, Kevin J., Egan, Michael A., Peyerl, Fred W., Santra, Sampa, Kuroda, Marcelo J., Schmitz, Jörn E., Beaudry, Kristin, Krivulka, Georgia R., Lifton, Michelle A., Gorgone, Darci A., Wolinsky, Steven M., Letvin, Norman L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Vaccines and Antiviral Agents
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC164797/
https://ncbi.nlm.nih.gov/pubmed/12805435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7367-7375.2003
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