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Viral Escape from Dominant Simian Immunodeficiency Virus Epitope-Specific Cytotoxic T Lymphocytes in DNA-Vaccinated Rhesus Monkeys

Virus-specific cytotoxic T lymphocytes (CTL) are critical for control of human immunodeficiency virus type 1 replication. However, viral escape from CTL recognition can undermine this immune control. Here we demonstrate the high frequency and pattern of viral escape from dominant epitope-specific CT...

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Publicado en:J Virol
Autores principales: Barouch, Dan H., Kunstman, Jennifer, Glowczwskie, Jennifer, Kunstman, Kevin J., Egan, Michael A., Peyerl, Fred W., Santra, Sampa, Kuroda, Marcelo J., Schmitz, Jörn E., Beaudry, Kristin, Krivulka, Georgia R., Lifton, Michelle A., Gorgone, Darci A., Wolinsky, Steven M., Letvin, Norman L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2003
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164797/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12805435/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.13.7367-7375.2003
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