טוען...
Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme
The virus-encoded nonstructural protein 5B (NS5B) of hepatitis C virus (HCV) is an RNA-dependent RNA polymerase and is absolutely required for replication of the virus. NS5B exhibits significant differences from cellular polymerases and therefore has become an attractive target for anti-HCV therapy....
שמור ב:
Main Authors: | , , , , , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
American Society for Microbiology
2003
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164784/ https://ncbi.nlm.nih.gov/pubmed/12805457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.13.7575-7581.2003 |
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