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Two Ubiquitin-Conjugating Enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, Have Distinct Functions for Ubiquitination of Mitotic Cyclin

Cell cycle events are regulated by sequential activation and inactivation of Cdk kinases. Mitotic exit is accomplished by the inactivation of mitotic Cdk kinase, which is mainly achieved by degradation of cyclins. The ubiquitin-proteasome system is involved in this process, requiring APC/C (anaphase...

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Bibliographische Detailangaben
Hauptverfasser: Seino, Hiroaki, Kishi, Tsutomu, Nishitani, Hideo, Yamao, Fumiaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC164763/
https://ncbi.nlm.nih.gov/pubmed/12724408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3497-3505.2003
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