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Two Ubiquitin-Conjugating Enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, Have Distinct Functions for Ubiquitination of Mitotic Cyclin

Cell cycle events are regulated by sequential activation and inactivation of Cdk kinases. Mitotic exit is accomplished by the inactivation of mitotic Cdk kinase, which is mainly achieved by degradation of cyclins. The ubiquitin-proteasome system is involved in this process, requiring APC/C (anaphase...

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Bibliografiska uppgifter
Huvudupphovsmän: Seino, Hiroaki, Kishi, Tsutomu, Nishitani, Hideo, Yamao, Fumiaki
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC164763/
https://ncbi.nlm.nih.gov/pubmed/12724408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3497-3505.2003
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