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Two Ubiquitin-Conjugating Enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, Have Distinct Functions for Ubiquitination of Mitotic Cyclin

Cell cycle events are regulated by sequential activation and inactivation of Cdk kinases. Mitotic exit is accomplished by the inactivation of mitotic Cdk kinase, which is mainly achieved by degradation of cyclins. The ubiquitin-proteasome system is involved in this process, requiring APC/C (anaphase...

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Detalhes bibliográficos
Main Authors: Seino, Hiroaki, Kishi, Tsutomu, Nishitani, Hideo, Yamao, Fumiaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164763/
https://ncbi.nlm.nih.gov/pubmed/12724408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.10.3497-3505.2003
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